File an unemployment claim as soon as you are separated from your employer.
UInteract, the online claim filing system is mobile friendly and available 24 hours a day. You may use UInteract to file your initial claim and your weekly request for payment by visiting https://uinteract.labor.mo.gov.
For questions or assistance, Regional Claims Centers (RCC) representatives are available from 8 a.m. to 5 p.m. Central Time, Monday through Friday, except holidays. Calls are answered in the order that they are received.
Jefferson City 573-751-9040
Kansas City 816-889-3101
St. Louis 314-340-4950
Outside Local Calling Area 800-320-2519
If the phone lines are busy when you call, please try again in a few minutes. Once you are in line to speak with a representative, do not hang up and call back. That will only increase your wait time by putting you again at the back of the line.